Acetylcysteine in kerato-conjunctivitis sicca.
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Acetylcysteine in kerato-conjunctivitis sicca.
KERATO-CONJUNCTIVITIS sicca is the condition which follows a reduction of secretion by the main and accessory lacrimal glands, and is characterized by interpalpebral staining of the bulbar conjunctiva with rose Bengal, punctate corneal staining with punctate opacities in Bowman's zone, the presence of thick stringy mucous strands in the lower fornices, and corneal filaments, the latter being ne...
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Although the ophthalmic lesions which constitute kerato-conjunctivitis sicca have long been known, the nature of the condition has remained obscure. Duke-Elder (1930) reviewed those rare cases in which lesions of the lacrimal secretary nerves or of the gland parenchyma (including congenital aplasia, surgical extirpation, infiltrations by sarcoid, leu-kaemic or malignant tissue) resulted in defi...
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KERATO-CONJUNCTIVITIS sicca is more often seen by and is of more interest to the ophthalmologist than the physician. It is little known and yet not uncommon. The usual syndrome is one affecting mainly middle-aged women and consisting of kerato-conjunctivitis sicca, rhinitis sicca, xerostoma, pharyngitis sicca, and parotid enlargement, and frequently including a chronic polyarthritis (Sjogren's ...
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The presumptive diagnosis was made on clinical grounds in the majority of cases, the signs and symptoms being those usually described-redness and discomfort, tenacious mucous discharge, and corneal erosions and filaments. Confirmation was obtained by the measurement of the lacrimal secretion by the filter-paper test (Schirmer, 1903) and in doubtful cases by staining with rose bengal. The relati...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1968
ISSN: 0007-1161
DOI: 10.1136/bjo.52.4.310